Thiazolidinediones inhibit the progression of established hypertension in the Dahl salt-sensitive rat.

Bolten, Charles W; Payne, Maria A; McDonald, William G; Blanner, Patrick M; Chott, Robert C; Ghosh, Sarbani; Arhancet, Graciela B; Staten, Nicholas R; Gulve, Eric A; Sullivan, Patrick M; Hromockyj, Alexander E; Colca, Jerry R

Bolten, Charles W; Payne, Maria A; McDonald, William G; Blanner, Patrick M; Chott, Robert C; Ghosh, Sarbani; Arhancet, Graciela B; Staten, Nicholas R; Gulve, Eric A; Sullivan, Patrick M; Hromockyj, Alexander E; Colca, Jerry R.

Affiliation

Bolten CW; Discovery Research, Pfizer Corporation, 700 Chesterfield Parkway West, Chesterfield, MO 63017, USA. charles.w.bolten@pfizer.com

Diab Vasc Dis Res ; 4(2): 117-23, 2007 Jun.

Article in En | MEDLINE | ID: mdl-17654445

Subject(s)

Antihypertensive Agents/pharmacology; Blood Pressure/drug effects; Hypertension/drug therapy; Pyridines/pharmacology; Thiazolidinediones/pharmacology; Adiponectin/blood; Animals; Antihypertensive Agents/pharmacokinetics; Antihypertensive Agents/therapeutic use; Blood Glucose/drug effects; Disease Models, Animal; Disease Progression; Heart Rate/drug effects; Hypertension/chemically induced; Hypertension/metabolism; Hypertension/physiopathology; Insulin/blood; Lipids/blood; Male; PPAR gamma/agonists; PPAR gamma/metabolism; Pyridines/pharmacokinetics; Pyridines/therapeutic use; Rats; Rats, Inbred Dahl; Rosiglitazone; Sodium Chloride, Dietary; Thiazolidinediones/pharmacokinetics; Thiazolidinediones/therapeutic use

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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Blood Pressure / Thiazolidinediones / Hypertension / Antihypertensive Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Diab Vasc Dis Res Journal subject: ANGIOLOGIA / ENDOCRINOLOGIA Year: 2007 Document type: Article Affiliation country: United States Country of publication: United kingdom

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