The cisplatin-irradiation combination suggests that apoptosis is not a major determinant of clonogenic death.

Lo Nigro, Cristiana; Arnolfo, Elena; Taricco, Enrico; Fruttero, Adriana; Russi, Elvio Grazioso; Lucio, Francesco; Ribero, Silvana; Comino, Alberto; Merlano, Marco; Ungari, Silvana

Lo Nigro, Cristiana; Arnolfo, Elena; Taricco, Enrico; Fruttero, Adriana; Russi, Elvio Grazioso; Lucio, Francesco; Ribero, Silvana; Comino, Alberto; Merlano, Marco; Ungari, Silvana.

Affiliation

Lo Nigro C; Molecular Biology Unit, Azienda Ospedaliera S. Croce e Carle, Cuneo, Italy.

Anticancer Drugs ; 18(6): 659-67, 2007 Jul.

Article in En | MEDLINE | ID: mdl-17762394

Subject(s)

Antineoplastic Agents/pharmacology; Apoptosis; Cisplatin/pharmacology; Radiation, Ionizing; Animals; Apoptosis/drug effects; Apoptosis/radiation effects; Cell Cycle/drug effects; Cell Cycle/radiation effects; Cell Line, Tumor; Cell Survival/drug effects; Cell Survival/radiation effects; Flow Cytometry; Gene Expression/drug effects; Mice; Necrosis; RNA, Messenger/genetics; Reverse Transcriptase Polymerase Chain Reaction; Tumor Stem Cell Assay; Tumor Suppressor Protein p53/biosynthesis; Tumor Suppressor Protein p53/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Radiation, Ionizing / Cisplatin / Apoptosis / Antineoplastic Agents Limits: Animals Language: En Journal: Anticancer Drugs Journal subject: ANTINEOPLASICOS Year: 2007 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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