Inter-alpha-trypsin inhibitor attenuates complement activation and complement-induced lung injury.

Garantziotis, Stavros; Hollingsworth, John W; Ghanayem, Rami B; Timberlake, Sarah; Zhuo, Lisheng; Kimata, Koji; Schwartz, David A

Garantziotis, Stavros; Hollingsworth, John W; Ghanayem, Rami B; Timberlake, Sarah; Zhuo, Lisheng; Kimata, Koji; Schwartz, David A.

Affiliation

Garantziotis S; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. garan001@mc.duke.edu

J Immunol ; 179(6): 4187-92, 2007 Sep 15.

Article in En | MEDLINE | ID: mdl-17785858

Subject(s)

Alpha-Globulins/physiology; Complement Activation/immunology; Complement Inactivator Proteins/physiology; Complement System Proteins/toxicity; Lung/immunology; Lung/pathology; Alpha-Globulins/deficiency; Alpha-Globulins/genetics; Alpha-Globulins/metabolism; Animals; Complement Activation/genetics; Complement Inactivator Proteins/deficiency; Complement Inactivator Proteins/genetics; Complement Inactivator Proteins/metabolism; Complement System Proteins/metabolism; Female; Immune Complex Diseases/immunology; Immune Complex Diseases/metabolism; Immune Complex Diseases/pathology; Immune Complex Diseases/prevention & control; Lung/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phagocytosis/immunology; Protein Binding/immunology; Protein Subunits/deficiency; Protein Subunits/genetics; Protein Subunits/metabolism; Protein Subunits/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Alpha-Globulins / Complement System Proteins / Complement Inactivator Proteins / Complement Activation / Lung Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

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