Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus.

Wermeling, Fredrik; Chen, Yunying; Pikkarainen, Timo; Scheynius, Annika; Winqvist, Ola; Izui, Shozo; Ravetch, Jeffrey V; Tryggvason, Karl; Karlsson, Mikael C I

Wermeling, Fredrik; Chen, Yunying; Pikkarainen, Timo; Scheynius, Annika; Winqvist, Ola; Izui, Shozo; Ravetch, Jeffrey V; Tryggvason, Karl; Karlsson, Mikael C I.

Affiliation

Wermeling F; Department of Medicine, Karolinska Institutet, Stockholm 171 76, Sweden.

J Exp Med ; 204(10): 2259-65, 2007 Oct 01.

Article in En | MEDLINE | ID: mdl-17893199

Subject(s)

Apoptosis/immunology; Autoantibodies/immunology; Immune Tolerance/immunology; Lupus Erythematosus, Systemic/diagnosis; Lupus Erythematosus, Systemic/immunology; Receptors, Scavenger/immunology; Adult; Animals; Autoantigens/immunology; Humans; Macrophages/immunology; Mice; Mice, Knockout; Receptors, Immunologic/deficiency; Receptors, Immunologic/genetics; Receptors, Immunologic/immunology; Receptors, Immunologic/metabolism; Receptors, Scavenger/classification; Receptors, Scavenger/deficiency; Receptors, Scavenger/genetics; Spleen/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoantibodies / Apoptosis / Receptors, Scavenger / Immune Tolerance / Lupus Erythematosus, Systemic Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Animals / Humans Language: En Journal: J Exp Med Year: 2007 Document type: Article Affiliation country: Sweden Country of publication: United States

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