SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a.

Deb, Arjun; Davis, Bryce H; Guo, Jian; Ni, Aiguo; Huang, Jing; Zhang, Zhiping; Mu, Hui; Dzau, Victor J

Deb, Arjun; Davis, Bryce H; Guo, Jian; Ni, Aiguo; Huang, Jing; Zhang, Zhiping; Mu, Hui; Dzau, Victor J.

Affiliation

Deb A; Division of Cardiovascular Diseases and Mandel Center for Hypertension & Atherosclerosis Research, Department of Medicine, GSRB 2, Box 3178, Duke University Medical Center, Durham, North Carolina 27710, USA. arjundeb@med.unc.edu

Stem Cells ; 26(1): 35-44, 2008 Jan.

Article in En | MEDLINE | ID: mdl-17916803

Subject(s)

Cell Differentiation/physiology; Embryonic Stem Cells/cytology; Gene Expression Regulation, Developmental; Membrane Proteins/metabolism; Myocytes, Cardiac/cytology; Wnt Proteins/genetics; Animals; Blotting, Western; Cell Line, Tumor; Embryonic Stem Cells/metabolism; Feedback, Physiological; Fluorescent Antibody Technique; Heart/embryology; Mice; Myocytes, Cardiac/metabolism; Pluripotent Stem Cells/cytology; Pluripotent Stem Cells/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Transfection; Wnt Proteins/metabolism; Wnt3 Protein; Wnt3A Protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Differentiation / Gene Expression Regulation, Developmental / Myocytes, Cardiac / Wnt Proteins / Embryonic Stem Cells / Membrane Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Stem Cells Year: 2008 Document type: Article Affiliation country: United States

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