Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism.

Rodríguez-Antona, C; Niemi, M; Backman, J T; Kajosaari, L I; Neuvonen, P J; Robledo, M; Ingelman-Sundberg, M

Rodríguez-Antona, C; Niemi, M; Backman, J T; Kajosaari, L I; Neuvonen, P J; Robledo, M; Ingelman-Sundberg, M.

Affiliation

Rodríguez-Antona C; Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden. cristina.rodriguez-antona@cnio.es

Pharmacogenomics J ; 8(4): 268-77, 2008 Aug.

Article in En | MEDLINE | ID: mdl-17923851

Subject(s)

Aryl Hydrocarbon Hydroxylases/genetics; Carbamates/metabolism; Haplotypes/genetics; Paclitaxel/metabolism; Piperidines/metabolism; Aryl Hydrocarbon Hydroxylases/metabolism; Aryl Hydrocarbon Hydroxylases/physiology; Carbamates/pharmacology; Cytochrome P-450 CYP2C8; Genetic Variation/drug effects; Genetic Variation/genetics; Haplotypes/drug effects; Humans; Paclitaxel/pharmacology; Piperidines/pharmacology; White People/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Haplotypes / Carbamates / Aryl Hydrocarbon Hydroxylases / Paclitaxel Limits: Humans Language: En Journal: Pharmacogenomics J Journal subject: BIOLOGIA MOLECULAR / FARMACOLOGIA Year: 2008 Document type: Article Affiliation country: Sweden

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