Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response.

Feld, Jordan J; Nanda, Santosh; Huang, Ying; Chen, Weiping; Cam, Maggie; Pusek, Susan N; Schweigler, Lisa M; Theodore, Dickens; Zacks, Steven L; Liang, T Jake; Fried, Michael W

Feld, Jordan J; Nanda, Santosh; Huang, Ying; Chen, Weiping; Cam, Maggie; Pusek, Susan N; Schweigler, Lisa M; Theodore, Dickens; Zacks, Steven L; Liang, T Jake; Fried, Michael W.

Affiliation

Feld JJ; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.

Hepatology ; 46(5): 1548-63, 2007 Nov.

Article in En | MEDLINE | ID: mdl-17929300

Subject(s)

Antiviral Agents/therapeutic use; Gene Expression/drug effects; Hepatitis C, Chronic/drug therapy; Interferon-alpha/therapeutic use; Polyethylene Glycols/therapeutic use; Ribavirin/therapeutic use; Adult; Antiviral Agents/pharmacology; Biopsy; Case-Control Studies; Cluster Analysis; Drug Therapy, Combination; Female; Gene Expression Profiling; Hepatitis C, Chronic/pathology; Humans; Interferon alpha-2; Interferon-alpha/pharmacology; Liver/drug effects; Liver/metabolism; Liver/pathology; Male; Middle Aged; Polyethylene Glycols/pharmacology; Polymerase Chain Reaction; Recombinant Proteins; Ribavirin/pharmacology; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Polyethylene Glycols / Ribavirin / Gene Expression / Interferon-alpha / Hepatitis C, Chronic Type of study: Clinical_trials / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Hepatology Year: 2007 Document type: Article Affiliation country: United States Country of publication: United States

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