WY-50, 295 tromethamine: an orally active 5-lipoxygenase inhibitor with anti-allergic activity.

Weichman, B M; Berkenkopf, J W; Chang, J Y; Heaslip, R J; Kreft, A F; Lewis, A J; Musser, J H; Grimes, D

Weichman, B M; Berkenkopf, J W; Chang, J Y; Heaslip, R J; Kreft, A F; Lewis, A J; Musser, J H; Grimes, D.

Affiliation

Weichman BM; Wyeth-Ayerst Research, Princeton, New Jersey 08543-8000.

Agents Actions Suppl ; 34: 201-9, 1991.

Article in En | MEDLINE | ID: mdl-1793064

Subject(s)

Hypersensitivity/physiopathology; Lipoxygenase Inhibitors/pharmacology; Naphthaleneacetic Acids/pharmacology; Quinolines/pharmacology; Administration, Oral; Animals; Antigens/immunology; Bronchoconstriction/drug effects; Guinea Pigs; Leukotrienes/biosynthesis; Muscle Contraction/drug effects; SRS-A/pharmacology; Trachea/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Lipoxygenase Inhibitors / Hypersensitivity / Naphthaleneacetic Acids Limits: Animals Language: En Journal: Agents Actions Suppl Year: 1991 Document type: Article

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