Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase.

Doyle, Sarah L; Jefferies, Caroline A; Feighery, Con; O'Neill, Luke A J

Doyle, Sarah L; Jefferies, Caroline A; Feighery, Con; O'Neill, Luke A J.

Affiliation

Doyle SL; School of Biochemistry and Immunology, Department of Immunology, Trinity College Dublin, Dublin 2, Ireland. Sarah.Doyle@tcd.ie

J Biol Chem ; 282(51): 36953-60, 2007 Dec 21.

Article in En | MEDLINE | ID: mdl-17932028

Subject(s)

DNA, Viral/immunology; Monocytes/immunology; Protein-Tyrosine Kinases/immunology; RNA, Viral/immunology; Toll-Like Receptor 8/immunology; Toll-Like Receptor 9/immunology; Virus Diseases/immunology; Agammaglobulinaemia Tyrosine Kinase; Agammaglobulinemia/genetics; Agammaglobulinemia/immunology; Cell Line; CpG Islands/immunology; DNA, Bacterial/immunology; Genetic Diseases, X-Linked/genetics; Genetic Diseases, X-Linked/immunology; Genetic Predisposition to Disease; Humans; Imidazoles/pharmacology; Interleukin-6/genetics; Interleukin-6/immunology; Phosphorylation/drug effects; Protein-Tyrosine Kinases/genetics; Toll-Like Receptor 8/genetics; Toll-Like Receptor 9/genetics; Virus Diseases/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Virus Diseases / DNA, Viral / RNA, Viral / Monocytes / Toll-Like Receptor 9 / Toll-Like Receptor 8 Limits: Humans Language: En Journal: J Biol Chem Year: 2007 Document type: Article Affiliation country: Ireland Country of publication: United States

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