Evolution of cell-based reagent provision.
Drug Discov Today
; 12(19-20): 820-5, 2007 Oct.
Article
in En
| MEDLINE
| ID: mdl-17933682
Cell-based screening is now part of all stages of drug discovery, and therefore, cell supply is a rate-limiting step. Reagent provision groups have responded by exploiting automation and new concepts such as frozen cells to ease the constraint and increase quality and flexibility of cell supply. With increasing numbers of projects to support, reagent development is now perceived as a new bottleneck. In this review, we describe a new operating model that has emerged at Pfizer UK addressing reagent development and cell supply issues without growing headcount, by complementing the application of internal expertise with use of contract research organisations.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Drug Design
/
Cell Line
/
Cell Culture Techniques
/
Indicators and Reagents
Limits:
Animals
/
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
Drug Discov Today
Journal subject:
FARMACOLOGIA
/
TERAPIA POR MEDICAMENTOS
Year:
2007
Document type:
Article
Country of publication:
United kingdom