Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells.

Nieto-Miguel, Teresa; Fonteriz, Rosalba I; Vay, Laura; Gajate, Consuelo; López-Hernández, Silvia; Mollinedo, Faustino

Nieto-Miguel, Teresa; Fonteriz, Rosalba I; Vay, Laura; Gajate, Consuelo; López-Hernández, Silvia; Mollinedo, Faustino.

Affiliation

Nieto-Miguel T; Centro de Investigación del Cáncer, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas-Universidad de Salamanca, Salamanca, Spain.

Cancer Res ; 67(21): 10368-78, 2007 Nov 01.

Article in En | MEDLINE | ID: mdl-17974980

Subject(s)

Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Endoplasmic Reticulum/drug effects; Neoplasms/drug therapy; Phospholipid Ethers/pharmacology; Calcium/metabolism; Caspases/physiology; Choline-Phosphate Cytidylyltransferase/antagonists & inhibitors; Endoplasmic Reticulum/metabolism; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases/metabolism; MAP Kinase Kinase Kinase 5/physiology; Neoplasms/metabolism; Neoplasms/pathology; Phosphatidylcholines/biosynthesis; Protein Synthesis Inhibitors/pharmacology; bcl-2 Homologous Antagonist-Killer Protein/physiology; bcl-2-Associated X Protein/physiology; bcl-X Protein/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Phospholipid Ethers / Apoptosis / Endoplasmic Reticulum / Neoplasms / Antineoplastic Agents Limits: Humans Language: En Journal: Cancer Res Year: 2007 Document type: Article Affiliation country: Spain Country of publication: United States

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