Cluster of Staphylococcus aureus and dengue co-infection in Singapore.
Ann Acad Med Singap
; 36(10): 847-50, 2007 Oct.
Article
in En
| MEDLINE
| ID: mdl-17987236
ABSTRACT
INTRODUCTION:
Singapore saw a resurgence of dengue infections in 2005. Concurrent bacterial co-infections in dengue is rare. CLINICAL PICTURE We report a cluster of serious methicillin-susceptible Staphylococcus aureus (MSSA) bacteraemia or severe soft tissue infection in 5 epidemiologically linked construction workers presenting with dengue and non-resolving fever. TREATMENT Surgical intervention was indicated in 4 of the 5 patients despite appropriate antistaphylococcal therapy.OUTCOME:
All but 1 patient were eventually discharged. Clonality and Panton-Valentine leucocidin genes were not demonstrated. Epidemiological investigations suggested that occupational contact dermatitis could have predisposed the patients to this opportunistic co-infection.CONCLUSION:
Clinicians need to be vigilant to unusual manifestations of dengue which may signal a concomitant aetiology.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Staphylococcal Infections
/
Dengue
Limits:
Adult
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
En
Journal:
Ann Acad Med Singap
Year:
2007
Document type:
Article
Affiliation country:
Singapore