Direct 99m Tc labeling of Herceptin (trastuzumab) by 99m Tc(I) tricarbonyl ion.

Chen, Wan-Jou; Yen, Chao-Liang; Lo, Su-Tang; Chen, Kuo-Ting; Lo, Jem-Mau

Chen, Wan-Jou; Yen, Chao-Liang; Lo, Su-Tang; Chen, Kuo-Ting; Lo, Jem-Mau.

Affiliation

Chen WJ; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu 30013, Taiwan.

Appl Radiat Isot ; 66(3): 340-5, 2008 Mar.

Article in En | MEDLINE | ID: mdl-17996452

Subject(s)

Antibodies, Monoclonal/chemistry; Antineoplastic Agents/chemistry; Radiopharmaceuticals/chemical synthesis; Technetium Compounds/chemical synthesis; Technetium/chemistry; Antibodies, Monoclonal/pharmacokinetics; Antibodies, Monoclonal/physiology; Antibodies, Monoclonal, Humanized; Antineoplastic Agents/pharmacokinetics; Antineoplastic Agents/pharmacology; Binding, Competitive; Breast Neoplasms/drug therapy; Breast Neoplasms/metabolism; Breast Neoplasms/radiotherapy; Cell Line, Tumor; Female; Humans; Isotope Labeling/methods; Radiopharmaceuticals/pharmacokinetics; Radiopharmaceuticals/pharmacology; Technetium Compounds/pharmacokinetics; Technetium Compounds/pharmacology; Trastuzumab

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Collection: 01-internacional Database: MEDLINE Main subject: Technetium / Technetium Compounds / Radiopharmaceuticals / Antibodies, Monoclonal / Antineoplastic Agents Limits: Female / Humans Language: En Journal: Appl Radiat Isot Journal subject: MEDICINA NUCLEAR / SAUDE AMBIENTAL Year: 2008 Document type: Article Affiliation country: Taiwan

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