Role of the sodium-dependent phosphate cotransporters and absorptive endocytosis in the uptake of low concentrations of uranium and its toxicity at higher concentrations in LLC-PK1 cells.

Muller, Dany S; Houpert, Pascale; Cambar, Jean; Hengé-Napoli, Marie-Hélène

Muller, Dany S; Houpert, Pascale; Cambar, Jean; Hengé-Napoli, Marie-Hélène.

Affiliation

Muller DS; Institut de Radioprotection et de Sûreté Nucléaire, Laboratoire de Radiotoxicologie Expérimentale, BP-166, 26702 Pierrelatte Cedex, France. dany.muller@kcl.ac.uk

Toxicol Sci ; 101(2): 254-62, 2008 Feb.

Article in En | MEDLINE | ID: mdl-17998273

Subject(s)

Endocytosis; Sodium-Phosphate Cotransporter Proteins, Type IIa/physiology; Uranyl Nitrate; Animals; Biological Transport; Cell Survival/drug effects; Dose-Response Relationship, Drug; Endocytosis/drug effects; Foscarnet/pharmacology; Kinetics; LLC-PK1 Cells; Microscopy, Electron, Transmission; Sodium-Phosphate Cotransporter Proteins, Type IIa/antagonists & inhibitors; Sodium-Phosphate Cotransporter Proteins, Type IIa/metabolism; Swine; Uranyl Nitrate/metabolism; Uranyl Nitrate/toxicity

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Collection: 01-internacional Database: MEDLINE Main subject: Uranyl Nitrate / Endocytosis / Sodium-Phosphate Cotransporter Proteins, Type IIa Limits: Animals Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2008 Document type: Article Affiliation country: France Country of publication: United States

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