Up-regulation of p21CIP1 expression mediated by ERK-dependent and -independent pathways contributes to hepatocyte growth factor-induced inhibition of HepG2 hepatoma cell proliferation.

Shirako, Erika; Hirayama, Naoki; Tsukada, Yu-ichi; Tanaka, Toshiaki; Kitamura, Naomi

Shirako, Erika; Hirayama, Naoki; Tsukada, Yu-ichi; Tanaka, Toshiaki; Kitamura, Naomi.

Affiliation

Shirako E; Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Nagatsuta, Midori-ku, Yokohama 226-8501, Japan.

J Cell Biochem ; 104(1): 176-88, 2008 May 01.

Article in En | MEDLINE | ID: mdl-18004740

Subject(s)

Carcinoma, Hepatocellular/pathology; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21/genetics; Extracellular Signal-Regulated MAP Kinases/metabolism; Hepatocyte Growth Factor/physiology; Cell Line, Tumor; ErbB Receptors; Humans; Signal Transduction; Up-Regulation

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Collection: 01-internacional Database: MEDLINE Main subject: Hepatocyte Growth Factor / Carcinoma, Hepatocellular / Extracellular Signal-Regulated MAP Kinases / Cell Proliferation / Cyclin-Dependent Kinase Inhibitor p21 Limits: Humans Language: En Journal: J Cell Biochem Year: 2008 Document type: Article Affiliation country: Japan Country of publication: United States

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