The use of deoxycholic acid to enhance the oral bioavailability of biodegradable nanoparticles.

Samstein, Robert M; Perica, Karlo; Balderrama, Fanor; Look, Michael; Fahmy, Tarek M

Samstein, Robert M; Perica, Karlo; Balderrama, Fanor; Look, Michael; Fahmy, Tarek M.

Affiliation

Samstein RM; Department of Biomedical Engineering, Yale University, 55 Prospect St., New Haven, CT 06511, USA.

Biomaterials ; 29(6): 703-8, 2008 Feb.

Article in En | MEDLINE | ID: mdl-18006053

Subject(s)

Deoxycholic Acid/administration & dosage; Lactic Acid/pharmacokinetics; Nanoparticles; Polyglycolic Acid/pharmacokinetics; Polymers/pharmacokinetics; Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Humans; Mice; Polylactic Acid-Polyglycolic Acid Copolymer

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Collection: 01-internacional Database: MEDLINE Main subject: Polyglycolic Acid / Polymers / Lactic Acid / Deoxycholic Acid / Nanoparticles Limits: Animals / Humans Language: En Journal: Biomaterials Year: 2008 Document type: Article Affiliation country: United States Country of publication: Netherlands

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