Collagen fiber and versican distribution within the lamina propria of fetal vocal folds.
Laryngoscope
; 118(2): 371-4, 2008 Feb.
Article
in En
| MEDLINE
| ID: mdl-18030168
ABSTRACT
OBJECTIVES:
To analyze the presence and distribution of collagen fibers and versican in human vocal fold lamina propria of fetal larynges. STUDYDESIGN:
Cross sectional analysis of cadaveric vocal folds of human fetuses.METHODS:
Seven fetal larynges obtained from 28- to 36-week-old fetuses were analyzed with the Picrosirius-polarization method, immunohistochemistry, and image analysis.RESULTS:
Collagen fibers within the lamina propria exhibited a monolaminar distribution pattern and spatial arrangement in "wicker basket." Versican distribution was larger in the superficial and intermediate layers when compared to the deep layer.CONCLUSION:
Our findings suggest that collagen and versican distribution and arrangement within the lamina propria in the developing fetus are important for vocalization at birth.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vocal Cords
/
Collagen
/
Versicans
/
Mucous Membrane
Type of study:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
Laryngoscope
Journal subject:
OTORRINOLARINGOLOGIA
Year:
2008
Document type:
Article
Affiliation country:
Brazil