Time-dependent formation of 8-oxo-deoxyguanosine in the lungs of mice exposed to cigarette smoke.

Thaiparambil, Jose T; Vadhanam, Manicka V; Srinivasan, Cidambi; Gairola, C Gary; Gupta, Ramesh C

Thaiparambil, Jose T; Vadhanam, Manicka V; Srinivasan, Cidambi; Gairola, C Gary; Gupta, Ramesh C.

Affiliation

Thaiparambil JT; James Graham Brown Cancer Center and Department of Pharmacology and Toxicology, University of Louisville, 580 South Preston Street, Louisville, Kentucky 40202, USA.

Chem Res Toxicol ; 20(12): 1737-40, 2007 Dec.

Article in En | MEDLINE | ID: mdl-18031018

Subject(s)

DNA Damage; Deoxyguanosine/analogs & derivatives; Inhalation Exposure/adverse effects; Lung/metabolism; Nicotiana/toxicity; Tobacco Smoke Pollution/adverse effects; 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine/metabolism; Female; Lung/drug effects; Mice; Mice, Inbred Strains; Oxidative Stress/drug effects; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Nicotiana / Tobacco Smoke Pollution / DNA Damage / Inhalation Exposure / Deoxyguanosine / Lung Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Chem Res Toxicol Journal subject: TOXICOLOGIA Year: 2007 Document type: Article Affiliation country: United States

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