A decrease in brain catecholamines prevents oxiracetam antagonism of the effects of scopolamine on memory and brain acetylcholine.

Giovannini, M G; Spignoli, G; Carlà, V; Pepeu, G

Giovannini, M G; Spignoli, G; Carlà, V; Pepeu, G.

Affiliation

Giovannini MG; Department of Preclinical and Clinical Pharmacology, University of Florence, Italy.

Pharmacol Res ; 24(4): 395-405, 1991 Dec.

Article in En | MEDLINE | ID: mdl-1805193

Subject(s)

Acetylcholine/metabolism; Brain/metabolism; Catecholamines/metabolism; Memory/drug effects; Psychotropic Drugs/pharmacology; Pyrrolidines/pharmacology; Scopolamine/antagonists & inhibitors; Animals; Avoidance Learning/drug effects; Brain/drug effects; Cerebral Cortex/metabolism; Conditioning, Psychological; Corpus Striatum/metabolism; Dopamine/metabolism; Haloperidol/pharmacology; Hippocampus/metabolism; Male; Norepinephrine/metabolism; Rats; Rats, Inbred Strains; Serotonin/metabolism; Substantia Nigra/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Psychotropic Drugs / Pyrrolidines / Scopolamine / Brain / Acetylcholine / Catecholamines / Memory Limits: Animals Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 1991 Document type: Article Affiliation country: Italy Country of publication: Netherlands

Search on Google

Add to My VHL

XML

PubMed Links