Effect of bosentan on the production of proinflammatory cytokines in a rat model of emphysema.

Gamze, Kilkil; Mehmet, Hamdi Muz; Deveci, Figen; Turgut, Teyfik; Ilhan, Fulya; Ozercan, Ibrahim

Gamze, Kilkil; Mehmet, Hamdi Muz; Deveci, Figen; Turgut, Teyfik; Ilhan, Fulya; Ozercan, Ibrahim.

Affiliation

Gamze K; Department of Chest Disease, Firat University, Faculty of Medicine, Elazig 23200, Turkey. gamkirkil@yahoo.com

Exp Mol Med ; 39(5): 614-20, 2007 Oct 31.

Article in En | MEDLINE | ID: mdl-18059137

Subject(s)

Cytokines/biosynthesis; Emphysema/drug therapy; Endothelin Receptor Antagonists; Sulfonamides/pharmacology; Animals; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Bosentan; Bronchoalveolar Lavage Fluid/cytology; Bronchoalveolar Lavage Fluid/immunology; Disease Models, Animal; Emphysema/etiology; Emphysema/immunology; Emphysema/pathology; Inflammation Mediators/metabolism; Lung/drug effects; Lung/immunology; Lung/pathology; Male; Pancreatic Elastase/administration & dosage; Pancreatic Elastase/toxicity; Rats; Rats, Wistar

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Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Cytokines / Emphysema / Endothelin Receptor Antagonists Type of study: Etiology_studies Limits: Animals Language: En Journal: Exp Mol Med Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2007 Document type: Article Affiliation country: Turkey Country of publication: United States

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