Detrimental effects of N-acetylcysteine plus desferoxamine combination in an experimental nephrotic syndrome model.

Bulucu, F; Oktenli, C; Kenar, L; Koc, B; Ocal, R; Karadurmus, N; Inal, V; Yamanel, L; Sanisoglu, Y S; Aydin, A

Bulucu, F; Oktenli, C; Kenar, L; Koc, B; Ocal, R; Karadurmus, N; Inal, V; Yamanel, L; Sanisoglu, Y S; Aydin, A.

Affiliation

Bulucu F; Department of Internal Medicine, Gülhane Military Medical Academy, Ankara, Turkey.

Int J Toxicol ; 26(6): 525-32, 2007.

Article in En | MEDLINE | ID: mdl-18066968

Subject(s)

Acetylcysteine/adverse effects; Antioxidants/adverse effects; Deferoxamine/adverse effects; Nephrotic Syndrome/drug therapy; Acetylcysteine/therapeutic use; Animals; Antioxidants/therapeutic use; Catalase/blood; Catalase/metabolism; Copper/blood; Deferoxamine/therapeutic use; Doxorubicin; Drug Therapy, Combination; Glutathione Peroxidase/blood; Glutathione Peroxidase/metabolism; Kidney/drug effects; Kidney/metabolism; Male; Nephrotic Syndrome/chemically induced; Nephrotic Syndrome/metabolism; Rats; Rats, Sprague-Dawley; Selenium/blood; Superoxide Dismutase/blood; Superoxide Dismutase/metabolism; Thiobarbituric Acid Reactive Substances/metabolism; Zinc/blood; Zinc/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Acetylcysteine / Deferoxamine / Nephrotic Syndrome / Antioxidants Limits: Animals Language: En Journal: Int J Toxicol Journal subject: TOXICOLOGIA Year: 2007 Document type: Article Affiliation country: Turkey Country of publication: United States

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