Oligomannan synthesis using ionic liquid supported glycosylation.
Org Lett
; 10(1): 145-8, 2008 Jan 03.
Article
in En
| MEDLINE
| ID: mdl-18069846
ABSTRACT
The synthesis of complex oligosaccharides has been a challenge for researchers. Herein, we describe a strategy for the synthesis of an activated oligomannan 1 that employs ionic liquid (IL) support glycosylation methodology on an IL-tagged mannosyl fluoride donor. This method is capable of rapidly producing linear alpha(1-->6) oligomannan thioglycosides in a convenient and cost-effective manner without the need of column purification after each glycosylation step.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Mannans
Language:
En
Journal:
Org Lett
Journal subject:
BIOQUIMICA
Year:
2008
Document type:
Article
Affiliation country:
United States