The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin.

Zanella, Isabella; Derosas, Manuela; Corrado, Marcella; Cocco, Emiliano; Cavadini, Patrizia; Biasiotto, Giorgio; Poli, Maura; Verardi, Rosanna; Arosio, Paolo

Zanella, Isabella; Derosas, Manuela; Corrado, Marcella; Cocco, Emiliano; Cavadini, Patrizia; Biasiotto, Giorgio; Poli, Maura; Verardi, Rosanna; Arosio, Paolo.

Affiliation

Zanella I; Dipartimento Materno Infantile e Tecnologie Biomediche, Università di Brescia, Viale Europa 11, Brescia, Italy.

Biochim Biophys Acta ; 1782(2): 90-8, 2008 Feb.

Article in En | MEDLINE | ID: mdl-18160053

Subject(s)

Apoferritins/genetics; Cell Proliferation/drug effects; Iron-Binding Proteins/antagonists & inhibitors; Iron-Binding Proteins/genetics; RNA, Small Interfering/pharmacology; Citrate (si)-Synthase/metabolism; Genes, Mitochondrial; HeLa Cells; Humans; Iron/metabolism; Iron-Binding Proteins/metabolism; Mitochondria/drug effects; Mitochondria/enzymology; Mitochondria/metabolism; RNA Interference/physiology; Succinate Dehydrogenase/metabolism; Transfection; Frataxin

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Collection: 01-internacional Database: MEDLINE Main subject: Apoferritins / Iron-Binding Proteins / RNA, Small Interfering / Cell Proliferation Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 2008 Document type: Article Affiliation country: Italy Country of publication: Netherlands

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