NMDA receptor activation potentiates inhibitory transmission through GABA receptor-associated protein-dependent exocytosis of GABA(A) receptors.

Marsden, Kurt C; Beattie, Jennifer B; Friedenthal, Jenna; Carroll, Reed C

Marsden, Kurt C; Beattie, Jennifer B; Friedenthal, Jenna; Carroll, Reed C.

Affiliation

Marsden KC; Dominick P. Purpura Department of Neuroscience, Rose Kennedy Center for Mental Retardation, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA.

J Neurosci ; 27(52): 14326-37, 2007 Dec 26.

Article in En | MEDLINE | ID: mdl-18160640

Subject(s)

Exocytosis/physiology; Glutamate Decarboxylase/metabolism; Inhibitory Postsynaptic Potentials/physiology; Microtubule-Associated Proteins/metabolism; Neurons/physiology; Receptors, GABA/physiology; Receptors, N-Methyl-D-Aspartate/physiology; Animals; Animals, Newborn; Biotinylation/methods; Cells, Cultured; Enzyme Inhibitors/pharmacology; Excitatory Amino Acid Agents/pharmacology; Exocytosis/drug effects; Hippocampus/cytology; In Vitro Techniques; Inhibitory Postsynaptic Potentials/drug effects; Inhibitory Postsynaptic Potentials/radiation effects; N-Methylaspartate/pharmacology; Neurons/drug effects; Patch-Clamp Techniques/methods; Protein Transport/drug effects; Protein Transport/physiology; RNA, Small Interfering/pharmacology; Rats; Rats, Sprague-Dawley; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, N-Methyl-D-Aspartate / Receptors, GABA / Exocytosis / Inhibitory Postsynaptic Potentials / Glutamate Decarboxylase / Microtubule-Associated Proteins / Neurons Type of study: Risk_factors_studies Limits: Animals Language: En Journal: J Neurosci Year: 2007 Document type: Article Affiliation country: United States

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