Lipophilic sugar nucleotide synthesis by structure-based design of nucleotidylyltransferase substrates.

Huestis, Malcolm P; Aish, Gaia A; Hui, Joseph P M; Soo, Evelyn C; Jakeman, David L

Huestis, Malcolm P; Aish, Gaia A; Hui, Joseph P M; Soo, Evelyn C; Jakeman, David L.

Affiliation

Huestis MP; College of Pharmacy, Dalhousie University, Halifax, Nova Scotia, CanadaB3H 3J5.

Org Biomol Chem ; 6(3): 477-84, 2008 Feb 07.

Article in En | MEDLINE | ID: mdl-18219417

Subject(s)

Nucleotides/chemical synthesis; Nucleotidyltransferases/metabolism; Pseudomonas aeruginosa/enzymology; Binding Sites; Crystallography, X-Ray; Glucose/analogs & derivatives; Glucose/chemistry; Glucose/metabolism; Models, Molecular; Nucleotidyltransferases/chemistry; Protein Structure, Secondary; Rhamnose/analogs & derivatives; Rhamnose/chemistry; Rhamnose/metabolism; Substrate Specificity; Sugar Phosphates; Thymine Nucleotides/chemistry; Thymine Nucleotides/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas aeruginosa / Nucleotides / Nucleotidyltransferases Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2008 Document type: Article Country of publication: United kingdom

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