Transitory or long-lasting immunity to Leishmania major infection: the result of immunogenicity and multicomponent properties of histone DNA vaccines.

Carrión, Javier; Folgueira, Cristina; Alonso, Carlos

Carrión, Javier; Folgueira, Cristina; Alonso, Carlos.

Affiliation

Carrión J; Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Cantoblanco E-28049, Madrid, Spain. jcarrion@cbm.uam.es

Vaccine ; 26(9): 1155-65, 2008 Feb 26.

Article in En | MEDLINE | ID: mdl-18255202

Subject(s)

Histones/immunology; Leishmania major/immunology; Leishmaniasis, Cutaneous/immunology; Protozoan Vaccines/immunology; Vaccines, DNA/immunology; Amino Acid Sequence; Animals; Antibodies, Protozoan/blood; COS Cells; Chlorocebus aethiops; Female; Histones/chemistry; Histones/genetics; Immunization; Leishmania major/genetics; Leishmania major/pathogenicity; Leishmaniasis, Cutaneous/parasitology; Leishmaniasis, Cutaneous/prevention & control; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nucleosomes; Plasmids; Protozoan Proteins/administration & dosage; Protozoan Proteins/genetics; Protozoan Proteins/immunology; Protozoan Vaccines/administration & dosage; Protozoan Vaccines/genetics; Th1 Cells/immunology; Th2 Cells/immunology; Vaccines, DNA/administration & dosage; Vaccines, DNA/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / Protozoan Vaccines / Leishmaniasis, Cutaneous / Leishmania major / Vaccines, DNA Limits: Animals Language: En Journal: Vaccine Year: 2008 Document type: Article Affiliation country: Spain Country of publication: Netherlands

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