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3-Amino-1,5-benzodiazepinones: potent, state-dependent sodium channel blockers with anti-epileptic activity.
Hoyt, Scott B; London, Clare; Wyvratt, Matthew J; Fisher, Michael H; Cashen, Doreen E; Felix, John P; Garcia, Maria L; Li, Xiaohua; Lyons, Kathryn A; Euan MacIntyre, D; Martin, William J; Priest, Birgit T; Smith, McHardy M; Warren, Vivien A; Williams, Brande S; Kaczorowski, Gregory J; Parsons, William H.
Affiliation
  • Hoyt SB; Department of Medicinal Chemistry, Merck Research Laboratories, PO Box 2000, RY 123-236, Rahway, NJ 07065-0900, USA.
Bioorg Med Chem Lett ; 18(6): 1963-6, 2008 Mar 15.
Article in En | MEDLINE | ID: mdl-18289851
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzodiazepinones / Sodium Channel Blockers / Epilepsy / Ether-A-Go-Go Potassium Channels / Anticonvulsants Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzodiazepinones / Sodium Channel Blockers / Epilepsy / Ether-A-Go-Go Potassium Channels / Anticonvulsants Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United kingdom