Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template.

Spencer, John; Gaffen, John; Griffin, Eric; Harper, Elaine A; Linney, Ian D; McDonald, Iain M; Roberts, Sonia P; Shaxted, Mark E; Adatia, Trushar; Bashall, Alan

Spencer, John; Gaffen, John; Griffin, Eric; Harper, Elaine A; Linney, Ian D; McDonald, Iain M; Roberts, Sonia P; Shaxted, Mark E; Adatia, Trushar; Bashall, Alan.

Affiliation

Spencer J; James Black Foundation, 68 Half Moon Lane, Dulwich, London SE24 9JE, UK.

Bioorg Med Chem ; 16(6): 2974-83, 2008 Mar 15.

Article in En | MEDLINE | ID: mdl-18289857

Subject(s)

Receptor, Cholecystokinin B/antagonists & inhibitors; Triazines/chemistry; Triazines/pharmacology; Animals; Benzazepines/chemistry; Benzazepines/pharmacology; Humans; Protein Binding; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazines / Receptor, Cholecystokinin B Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2008 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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