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Discovery of azetidinone acids as conformationally-constrained dual PPARalpha/gamma agonists.
Wang, Wei; Devasthale, Pratik; Farrelly, Dennis; Gu, Liqun; Harrity, Thomas; Cap, Michael; Chu, Cuixia; Kunselman, Lori; Morgan, Nathan; Ponticiello, Randy; Zebo, Rachel; Zhang, Litao; Locke, Kenneth; Lippy, Jonathan; O'Malley, Kevin; Hosagrahara, Vinayak; Zhang, Lisa; Kadiyala, Pathanjali; Chang, Chiehying; Muckelbauer, Jodi; Doweyko, Arthur M; Zahler, Robert; Ryono, Denis; Hariharan, Narayanan; Cheng, Peter T W.
Affiliation
  • Wang W; Metabolic Diseases Chemistry, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-5400, USA.
Bioorg Med Chem Lett ; 18(6): 1939-44, 2008 Mar 15.
Article in En | MEDLINE | ID: mdl-18291645
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azetidines / PPAR alpha / PPAR gamma Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azetidines / PPAR alpha / PPAR gamma Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United kingdom