Human blood dendritic cells from allergic subjects have impaired capacity to produce interferon-alpha via Toll-like receptor 9.

Tversky, J R; Le, T V; Bieneman, A P; Chichester, K L; Hamilton, R G; Schroeder, J T

Tversky, J R; Le, T V; Bieneman, A P; Chichester, K L; Hamilton, R G; Schroeder, J T.

Affiliation

Tversky JR; Department of Medicine, Johns Hopkins Asthma and Allergy Center, Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, MD 21224, USA. Jodytversky@yahoo.com

Clin Exp Allergy ; 38(5): 781-8, 2008 May.

Article in En | MEDLINE | ID: mdl-18318750

Subject(s)

Dendritic Cells/immunology; Dendritic Cells/pathology; Hypersensitivity, Immediate/immunology; Hypersensitivity, Immediate/physiopathology; Interferon-alpha/metabolism; Toll-Like Receptor 9/metabolism; Adult; Asthma/immunology; Asthma/physiopathology; CpG Islands/immunology; Dendritic Cells/metabolism; Female; Food Hypersensitivity/immunology; Food Hypersensitivity/physiopathology; Humans; Male; Middle Aged; Receptors, IgE/metabolism; Rhinitis, Allergic, Perennial/immunology; Rhinitis, Allergic, Perennial/physiopathology; Rhinitis, Allergic, Seasonal/immunology; Rhinitis, Allergic, Seasonal/physiopathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Interferon-alpha / Toll-Like Receptor 9 / Hypersensitivity, Immediate Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Exp Allergy Journal subject: ALERGIA E IMUNOLOGIA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United kingdom

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