Spatial and temporal heterogeneity of ventilator-associated lung injury after surfactant depletion.

Otto, Cynthia M; Markstaller, Klaus; Kajikawa, Osamu; Karmrodt, Jens; Syring, Rebecca S; Pfeiffer, Birgit; Good, Virginia P; Frevert, Charles W; Baumgardner, James E

Otto, Cynthia M; Markstaller, Klaus; Kajikawa, Osamu; Karmrodt, Jens; Syring, Rebecca S; Pfeiffer, Birgit; Good, Virginia P; Frevert, Charles W; Baumgardner, James E.

Affiliation

Otto CM; Departmrnt of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, USA.

J Appl Physiol (1985) ; 104(5): 1485-94, 2008 May.

Article in En | MEDLINE | ID: mdl-18323462

Subject(s)

Lung Injury; Oxygen/blood; Pulmonary Surfactants; Ventilators, Mechanical/adverse effects; Animals; Blood Gas Analysis; Calibration; Chemokine CCL2/metabolism; Chemokines/metabolism; Cytokines/metabolism; Enzyme-Linked Immunosorbent Assay; Female; Fluid Therapy; Interleukin-8/biosynthesis; Lung/pathology; Neutrophil Infiltration; Nitric Oxide Synthase Type II/biosynthesis; Peroxidase/metabolism; Pulmonary Edema/etiology; Pulmonary Edema/pathology; Rabbits; Respiratory Mechanics/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Pulmonary Surfactants / Ventilators, Mechanical / Lung Injury Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: J Appl Physiol (1985) Journal subject: FISIOLOGIA Year: 2008 Document type: Article Affiliation country: United States

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