Genotypic detection of acyclovir-resistant HSV-1: characterization of 67 ACV-sensitive and 14 ACV-resistant viruses.

Frobert, Emilie; Cortay, Jean-Claude; Ooka, Tadamasa; Najioullah, Fatiha; Thouvenot, Danielle; Lina, Bruno; Morfin, Florence

Frobert, Emilie; Cortay, Jean-Claude; Ooka, Tadamasa; Najioullah, Fatiha; Thouvenot, Danielle; Lina, Bruno; Morfin, Florence.

Affiliation

Frobert E; Laboratoire de Virologie, Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, Bron Cedex, Lyon, France. efrobert@sante.univ-lyon1.fr

Antiviral Res ; 79(1): 28-36, 2008 Jul.

Article in En | MEDLINE | ID: mdl-18336925

Subject(s)

Acyclovir/pharmacology; Drug Resistance, Viral; Herpes Simplex/virology; Herpesvirus 1, Human/drug effects; Herpesvirus 1, Human/isolation & purification; Polymerase Chain Reaction/methods; Adult; Child; Child, Preschool; DNA-Directed DNA Polymerase/genetics; Female; Genotype; Herpesvirus 1, Human/genetics; Humans; Male; Mutation; Polymorphism, Genetic; Sensitivity and Specificity; Sequence Analysis, DNA/methods; Thymidine Kinase/antagonists & inhibitors; Thymidine Kinase/genetics; Viral Proteins/antagonists & inhibitors; Viral Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acyclovir / Polymerase Chain Reaction / Herpesvirus 1, Human / Drug Resistance, Viral / Herpes Simplex Type of study: Diagnostic_studies / Evaluation_studies Limits: Adult / Child / Child, preschool / Female / Humans / Male Language: En Journal: Antiviral Res Year: 2008 Document type: Article Affiliation country: France

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