Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections.

Brickner, Steven J; Barbachyn, Michael R; Hutchinson, Douglas K; Manninen, Peter R

Brickner, Steven J; Barbachyn, Michael R; Hutchinson, Douglas K; Manninen, Peter R.

Affiliation

Brickner SJ; Pfizer Global Research and Development, Groton, Connecticut 06340, USA. steven.j.brickner@pfizer.com

J Med Chem ; 51(7): 1981-90, 2008 Apr 10.

Article in En | MEDLINE | ID: mdl-18338841

Subject(s)

Acetamides/classification; Acetamides/therapeutic use; Anti-Bacterial Agents/classification; Anti-Bacterial Agents/therapeutic use; Gram-Positive Bacterial Infections/drug therapy; Oxazolidinones/classification; Oxazolidinones/therapeutic use; Acetamides/chemistry; Animals; Anti-Bacterial Agents/chemistry; Drug Resistance, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gram-Positive Bacterial Infections / Oxazolidinones / Acetamides / Anti-Bacterial Agents Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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