Endoplasmic reticulum stress--a double edged sword for Z alpha-1 antitrypsin deficiency hepatoxicity.

Lawless, Matthew W; Mankan, Arun K; Gray, Steven G; Norris, Suzanne

Lawless, Matthew W; Mankan, Arun K; Gray, Steven G; Norris, Suzanne.

Affiliation

Lawless MW; Hepatology Research Division and Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, St. James Hospital, Dublin 8, Ireland. mlawles@tcd.ie

Int J Biochem Cell Biol ; 40(8): 1403-14, 2008.

Article in En | MEDLINE | ID: mdl-18353704

Subject(s)

Endoplasmic Reticulum/physiology; Liver Diseases/genetics; alpha 1-Antitrypsin Deficiency/physiopathology; Apoptosis/physiology; Endoplasmic Reticulum/pathology; Humans; Inflammation/complications; Liver/metabolism; Liver Diseases/physiopathology; Models, Biological; NF-kappa B/physiology; Phenotype; Protein Conformation; Protein Folding

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alpha 1-Antitrypsin Deficiency / Endoplasmic Reticulum / Liver Diseases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Int J Biochem Cell Biol Journal subject: BIOQUIMICA Year: 2008 Document type: Article Affiliation country: Ireland Country of publication: Netherlands

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