Thrombin-induced endothelial barrier disruption in intact microvessels: role of RhoA/Rho kinase-myosin phosphatase axis.

van Nieuw Amerongen, G P; Musters, R J P; Eringa, E C; Sipkema, P; van Hinsbergh, V W M

van Nieuw Amerongen, G P; Musters, R J P; Eringa, E C; Sipkema, P; van Hinsbergh, V W M.

Affiliation

van Nieuw Amerongen GP; Laboratory for Physiology, Institute for Cardiovascular Research, Vrije Universiteit University Medical Center, Amsterdam, The Netherlands. nieuwamerongen@vumc.nl

Am J Physiol Cell Physiol ; 294(5): C1234-41, 2008 May.

Article in En | MEDLINE | ID: mdl-18353893

Subject(s)

Endothelium, Vascular/physiology; Microcirculation/physiology; Myosin-Light-Chain Phosphatase/physiology; Thrombin/pharmacology; rho-Associated Kinases/physiology; rhoA GTP-Binding Protein/physiology; Animals; Concanavalin A/pharmacology; Endothelium, Vascular/drug effects; Humans; Microcirculation/drug effects; Rats; Rats, Wistar; Umbilical Veins/drug effects; Umbilical Veins/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelium, Vascular / Thrombin / RhoA GTP-Binding Protein / Myosin-Light-Chain Phosphatase / Rho-Associated Kinases / Microcirculation Limits: Animals / Humans Language: En Journal: Am J Physiol Cell Physiol Journal subject: FISIOLOGIA Year: 2008 Document type: Article Affiliation country: Netherlands Country of publication: United States

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