Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid.

Schneidewind, Arne; Brockman, Mark A; Sidney, John; Wang, Yaoyu E; Chen, Huabiao; Suscovich, Todd J; Li, Bin; Adam, Rahma I; Allgaier, Rachel L; Mothé, Bianca R; Kuntzen, Thomas; Oniangue-Ndza, Cesar; Trocha, Alicja; Yu, Xu G; Brander, Christian; Sette, Alessandro; Walker, Bruce D; Allen, Todd M

Schneidewind, Arne; Brockman, Mark A; Sidney, John; Wang, Yaoyu E; Chen, Huabiao; Suscovich, Todd J; Li, Bin; Adam, Rahma I; Allgaier, Rachel L; Mothé, Bianca R; Kuntzen, Thomas; Oniangue-Ndza, Cesar; Trocha, Alicja; Yu, Xu G; Brander, Christian; Sette, Alessandro; Walker, Bruce D; Allen, Todd M.

Affiliation

Schneidewind A; Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

J Virol ; 82(11): 5594-605, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18385228

Subject(s)

Capsid Proteins/immunology; Epitopes, T-Lymphocyte/immunology; HIV-1/immunology; HLA-B27 Antigen/immunology; T-Lymphocytes, Cytotoxic/immunology; Amino Acid Sequence; Base Sequence; Capsid Proteins/genetics; Capsid Proteins/metabolism; Cell Line; Epitopes, T-Lymphocyte/chemistry; HLA-B27 Antigen/genetics; HLA-B27 Antigen/metabolism; Humans; Mutation/genetics; Virus Replication/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / HLA-B27 Antigen / HIV-1 / Epitopes, T-Lymphocyte / Capsid Proteins Limits: Humans Language: En Journal: J Virol Year: 2008 Document type: Article Affiliation country: United States

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