Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs.

Holt, Lucy J; Basran, Amrik; Jones, Kate; Chorlton, Jennifer; Jespers, Laurent S; Brewis, Neil D; Tomlinson, Ian M

Holt, Lucy J; Basran, Amrik; Jones, Kate; Chorlton, Jennifer; Jespers, Laurent S; Brewis, Neil D; Tomlinson, Ian M.

Affiliation

Holt LJ; Domantis Limited, 315 Cambridge Science Park, Cambridge, CB4 0WG, UK. lucy.holt@domantis.com

Protein Eng Des Sel ; 21(5): 283-8, 2008 May.

Article in En | MEDLINE | ID: mdl-18387938

Subject(s)

Albumins/chemistry; Chemistry, Pharmaceutical/methods; Drug Industry/methods; Protein Engineering/methods; Amino Acid Sequence; Animals; Collagen/chemistry; Dose-Response Relationship, Drug; Drug Design; Humans; Interleukin 1 Receptor Antagonist Protein/chemistry; Mice; Molecular Sequence Data; Peptide Library; Rats; Sequence Homology, Amino Acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Engineering / Chemistry, Pharmaceutical / Albumins / Drug Industry Limits: Animals / Humans Language: En Journal: Protein Eng Des Sel Journal subject: BIOQUIMICA / BIOTECNOLOGIA Year: 2008 Document type: Article Affiliation country: United kingdom

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