A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver.

Wangensteen, Kirk J; Wilber, Andrew; Keng, Vincent W; He, Zhiying; Matise, Ilze; Wangensteen, Laura; Carson, Corey M; Chen, Yixin; Steer, Clifford J; McIvor, R Scott; Largaespada, David A; Wang, Xin; Ekker, Stephen C

Wangensteen, Kirk J; Wilber, Andrew; Keng, Vincent W; He, Zhiying; Matise, Ilze; Wangensteen, Laura; Carson, Corey M; Chen, Yixin; Steer, Clifford J; McIvor, R Scott; Largaespada, David A; Wang, Xin; Ekker, Stephen C.

Affiliation

Wangensteen KJ; The Arnold and Mabel Beckman Center for Transposon Research, Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA.

Hepatology ; 47(5): 1714-24, 2008 May.

Article in En | MEDLINE | ID: mdl-18435462

Subject(s)

Gene Expression Regulation; Liver/physiology; Amino Acid Substitution; Animals; Cell Line, Tumor; DNA, Complementary/genetics; Female; Genes, Reporter; Humans; Hydrolases/deficiency; Hydrolases/genetics; Intestinal Neoplasms; Liver/cytology; Liver/pathology; Liver Neoplasms/genetics; Luciferases/genetics; Mice; Oligonucleotide Array Sequence Analysis; Plasmids; Uterine Cervical Neoplasms; alpha 1-Antitrypsin/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Liver Limits: Animals / Female / Humans Language: En Journal: Hepatology Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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