Interleukin-6 receptor superantagonist Sant7 inhibits TGF-beta-induced proliferation of human lung fibroblasts.

Gallelli, L; Falcone, D; Pelaia, G; Renda, T; Terracciano, R; Malara, N; Vatrella, A; Sanduzzi, A; D'Agostino, B; Rossi, F; Vancheri, C; Maselli, R; Marsico, S A; Savino, R

Gallelli, L; Falcone, D; Pelaia, G; Renda, T; Terracciano, R; Malara, N; Vatrella, A; Sanduzzi, A; D'Agostino, B; Rossi, F; Vancheri, C; Maselli, R; Marsico, S A; Savino, R.

Affiliation

Gallelli L; Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Italy.

Cell Prolif ; 41(3): 393-407, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18435790

Subject(s)

Fibroblasts/cytology; Fibroblasts/drug effects; Interleukin-6/analogs & derivatives; Lung/cytology; Receptors, Interleukin-6/antagonists & inhibitors; Transforming Growth Factor beta1/antagonists & inhibitors; Cell Proliferation/drug effects; Cell Survival/drug effects; Cells, Cultured; Fibroblasts/enzymology; Humans; Interleukin-6/pharmacology; JNK Mitogen-Activated Protein Kinases/metabolism; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/metabolism; Phosphorylation/drug effects; Transforming Growth Factor beta1/pharmacology; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-6 / Receptors, Interleukin-6 / Transforming Growth Factor beta1 / Fibroblasts / Lung Limits: Humans Language: En Journal: Cell Prolif Year: 2008 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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