Paraffin-based 6-gene model predicts outcome in diffuse large B-cell lymphoma patients treated with R-CHOP.

Malumbres, Raquel; Chen, Jun; Tibshirani, Rob; Johnson, Nathalie A; Sehn, Laurie H; Natkunam, Yaso; Briones, Javier; Advani, Ranjana; Connors, Joseph M; Byrne, Gerald E; Levy, Ronald; Gascoyne, Randy D; Lossos, Izidore S

Malumbres, Raquel; Chen, Jun; Tibshirani, Rob; Johnson, Nathalie A; Sehn, Laurie H; Natkunam, Yaso; Briones, Javier; Advani, Ranjana; Connors, Joseph M; Byrne, Gerald E; Levy, Ronald; Gascoyne, Randy D; Lossos, Izidore S.

Affiliation

Malumbres R; Department of Medicine, Division of Hematology-Oncology and Molecular and Cellular Pharmacology, Sylvester Comprehensive Cancer Center, University of Miami, FL 33136, USA.

Blood ; 111(12): 5509-14, 2008 Jun 15.

Article in En | MEDLINE | ID: mdl-18445689

Subject(s)

Antibodies, Monoclonal/therapeutic use; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Lymphoma, Large B-Cell, Diffuse/drug therapy; Lymphoma, Large B-Cell, Diffuse/genetics; Models, Genetic; Antibodies, Monoclonal, Murine-Derived; Biopsy; Cyclophosphamide/therapeutic use; Doxorubicin/therapeutic use; Humans; Kaplan-Meier Estimate; Lymphoma, Large B-Cell, Diffuse/mortality; Lymphoma, Large B-Cell, Diffuse/pathology; Multivariate Analysis; Paraffin Embedding; Predictive Value of Tests; Prednisone/therapeutic use; Prognosis; Risk Factors; Rituximab; Treatment Outcome; Vincristine/therapeutic use

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Lymphoma, Large B-Cell, Diffuse / Models, Genetic / Antibodies, Monoclonal Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Blood Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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