The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals.

Kanazawa, Takayuki; Zappaterra, Mauro D; Hasegawa, Ayako; Wright, Ashley P; Newman-Smith, Erin D; Buttle, Karolyn F; McDonald, Kent; Mannella, Carmen A; van der Bliek, Alexander M

Kanazawa, Takayuki; Zappaterra, Mauro D; Hasegawa, Ayako; Wright, Ashley P; Newman-Smith, Erin D; Buttle, Karolyn F; McDonald, Kent; Mannella, Carmen A; van der Bliek, Alexander M.

Affiliation

Kanazawa T; Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.

PLoS Genet ; 4(2): e1000022, 2008 Feb 29.

Article in En | MEDLINE | ID: mdl-18454199

Subject(s)

Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/genetics; Caenorhabditis elegans/metabolism; Amino Acid Sequence; Animals; Caenorhabditis elegans/drug effects; Caenorhabditis elegans Proteins/chemistry; Caenorhabditis elegans Proteins/genetics; Drug Resistance/genetics; Dynamins/chemistry; Dynamins/genetics; Dynamins/metabolism; Free Radicals/metabolism; Free Radicals/toxicity; GTP Phosphohydrolases/genetics; GTP Phosphohydrolases/metabolism; GTP-Binding Proteins/genetics; Genes, Helminth; Humans; Mitochondria/metabolism; Mitochondria/ultrastructure; Mitochondrial Proteins/genetics; Models, Molecular; Molecular Sequence Data; Mutation; Optic Atrophy, Autosomal Dominant/etiology; Optic Atrophy, Autosomal Dominant/genetics; Optic Atrophy, Autosomal Dominant/metabolism; Oxidative Phosphorylation; Paraquat/toxicity; Phenotype; RNA Interference; Saccharomyces cerevisiae Proteins/genetics; Sequence Homology, Amino Acid; Superoxide Dismutase/genetics; Superoxide Dismutase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Caenorhabditis elegans / Caenorhabditis elegans Proteins Type of study: Etiology_studies Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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