Left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardia.
N Engl J Med
; 358(19): 2024-9, 2008 May 08.
Article
in En
| MEDLINE
| ID: mdl-18463378
ABSTRACT
Catecholaminergic polymorphic ventricular tachycardia is a potentially lethal disease characterized by adrenergically mediated ventricular arrhythmias manifested especially in children and teenagers. Beta-blockers are the cornerstone of therapy, but some patients do not have a complete response to this therapy and receive an implantable cardioverter-defibrillator (ICD). Given the nature of catecholaminergic polymorphic ventricular tachycardia, ICD shocks may trigger new arrhythmias, leading to the administration of multiple shocks. We describe the long-term efficacy of surgical left cardiac sympathetic denervation in three young adults with catecholaminergic polymorphic ventricular tachycardia, all of whom had symptoms before the procedure and were symptom-free afterward.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sympathectomy
/
Tachycardia, Ventricular
/
Heart
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Adolescent
/
Female
/
Humans
/
Male
Language:
En
Journal:
N Engl J Med
Year:
2008
Document type:
Article