Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model.

Stark, Kimberly L; Xu, Bin; Bagchi, Anindya; Lai, Wen-Sung; Liu, Hui; Hsu, Ruby; Wan, Xiang; Pavlidis, Paul; Mills, Alea A; Karayiorgou, Maria; Gogos, Joseph A

Stark, Kimberly L; Xu, Bin; Bagchi, Anindya; Lai, Wen-Sung; Liu, Hui; Hsu, Ruby; Wan, Xiang; Pavlidis, Paul; Mills, Alea A; Karayiorgou, Maria; Gogos, Joseph A.

Affiliation

Stark KL; Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, New York 10032, USA.

Nat Genet ; 40(6): 751-60, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18469815

Subject(s)

Behavior, Animal/physiology; Brain/physiology; Chromosome Deletion; Chromosomes, Human, Pair 22/genetics; Disease Models, Animal; MicroRNAs/biosynthesis; MicroRNAs/genetics; Animals; Cognition Disorders/genetics; Female; Gene Expression Profiling; Habituation, Psychophysiologic/genetics; Heterozygote; Humans; Learning Disabilities/genetics; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Phenotype; Proteins/physiology; RNA-Binding Proteins; Sensation Disorders/genetics; Spine/anatomy & histology; Spine/growth & development

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Behavior, Animal / Chromosomes, Human, Pair 22 / Brain / Chromosome Deletion / MicroRNAs / Disease Models, Animal Limits: Animals / Female / Humans / Male Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2008 Document type: Article Affiliation country: United States Country of publication: United States

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