[Gemtuzumab ozogamicin successfully induced molecular remission in relapsed therapy-related acute promyelocytic leukemia].
Rinsho Ketsueki
; 49(4): 270-2, 2008 Apr.
Article
in Ja
| MEDLINE
| ID: mdl-18516871
ABSTRACT
A 37-year-old woman was diagnosed with therapy-related acute promyelocytic leukemia (t-APL) in May 2006 after chemotherapy that included etoposide for ovarian cancer in November 2003. After treatment with all-trans retinoic acid in combination with chemotherapy, complete remission was attained. The patient was admitted on March 19, 2007 due to cerebral infarction and it was found that t-APL had recurred. Induction therapy with gemtuzumab ozogamicin (GO) was attempted. Molecular remission was attained without serious complication. GO is considered a promising agent to achieve molecular remission in patients with relapsed t-APL.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Leukemia, Promyelocytic, Acute
/
Etoposide
/
Aminoglycosides
/
Antibodies, Monoclonal
/
Antineoplastic Agents
/
Antineoplastic Agents, Phytogenic
Limits:
Adult
/
Female
/
Humans
Language:
Ja
Journal:
Rinsho Ketsueki
Year:
2008
Document type:
Article