T-2 toxin-induced apoptosis involving Fas, p53, Bcl-xL, Bcl-2, Bax and caspase-3 signaling pathways in human chondrocytes.

Chen, Jing-hong; Cao, Jun-ling; Chu, Yong-lie; Wang, Zhi-lun; Yang, Zhan-tian; Wang, Hong-lin

Chen, Jing-hong; Cao, Jun-ling; Chu, Yong-lie; Wang, Zhi-lun; Yang, Zhan-tian; Wang, Hong-lin.

Affiliation

Chen JH; Ministry of Education Key Laboratory of Environment and Genes related to Diseases, Institute of Endemic Diseases, School of Medicine, Xi'an Jiaotong University, Xi'an 710061, China. Jixiang46@163.com

J Zhejiang Univ Sci B ; 9(6): 455-63, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18543398

Subject(s)

Chondrocytes/drug effects; Chondrocytes/metabolism; T-2 Toxin/toxicity; Apoptosis/drug effects; Base Sequence; Blotting, Western; Caspase 3/genetics; Caspase 3/metabolism; Cell Proliferation/drug effects; Cells, Cultured; Chondrocytes/cytology; DNA Primers/genetics; Gene Expression/drug effects; Humans; Proto-Oncogene Proteins c-bcl-2/genetics; Proto-Oncogene Proteins c-bcl-2/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction/drug effects; Tumor Suppressor Protein p53/genetics; Tumor Suppressor Protein p53/metabolism; bcl-2-Associated X Protein/genetics; bcl-2-Associated X Protein/metabolism; bcl-X Protein/genetics; bcl-X Protein/metabolism; fas Receptor/genetics; fas Receptor/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-2 Toxin / Chondrocytes Limits: Humans Language: En Journal: J Zhejiang Univ Sci B Journal subject: BIOLOGIA / MEDICINA Year: 2008 Document type: Article Affiliation country: China Country of publication: China

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