[Shift in the content of immune cytokines in heart of mice under acoustic stress conditions and delta-sleep inducing peptide application].
Georgian Med News
; (158): 45-8, 2008 May.
Article
in Ru
| MEDLINE
| ID: mdl-18560040
ABSTRACT
Quantitative shifts in the content of interleukine-1, -2 and -6 of the myocardium of mice under the conditions of acoustic stress and delta-sleep inducing peptide action are studied. It has been shown that injection of delta-sleep inducing peptide has no effect on the level of interleukine-1 and -2 in the myocardial tissue, whereas the quantity of interleukine-6 increased. The level of interleukine-1- and -6 in the myocardium were increased and no significant changes were observed in the level of interleukine-2 under the noise action. Interleukine-1- and -2 were not detected in the hypophysis of experimental animals of all groups (intact, under acoustic stress, under delta-sleep inducing peptide application). The level of interleukine-6 in the hypothalamus decreased under conditions of acoustic stress, whereas administration of delta-sleep inducing peptide has no effect on its level. The obtained data are considered in the context of immune modulating properties of delta-sleep inducing peptide.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sleep Stages
/
Delta Sleep-Inducing Peptide
/
Interleukin-6
/
Interleukin-1
/
Interleukin-2
/
Heart Failure
/
Myocardium
/
Noise
Limits:
Animals
Language:
Ru
Journal:
Georgian Med News
Journal subject:
MEDICINA
Year:
2008
Document type:
Article