Differential roles of endothelin-1 ETA and ETB receptors and vasoactive intestinal polypeptide in regulation of the airways and the pulmonary vasculature in isolated rat lung.

Janosi, Tibor; Peták, Ferenc; Fontao, Fabienne; Morel, Denis R; Beghetti, Maurice; Habre, Walid

Janosi, Tibor; Peták, Ferenc; Fontao, Fabienne; Morel, Denis R; Beghetti, Maurice; Habre, Walid.

Affiliation

Janosi T; Paediatric Anaesthesia Unit, Geneva Children's Hospital, Rue Willy Donze 6, CH-1205 Geneva, Switzerland.

Exp Physiol ; 93(11): 1210-9, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18567602

Subject(s)

Antihypertensive Agents/pharmacology; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Hypertension, Pulmonary/drug therapy; Lung/drug effects; Oligopeptides/pharmacology; Peptides, Cyclic/pharmacology; Piperidines/pharmacology; Vasoactive Intestinal Peptide/pharmacology; Airway Resistance/drug effects; Animals; Bronchoconstriction/drug effects; Endothelin-1/metabolism; Hypertension, Pulmonary/metabolism; Hypertension, Pulmonary/physiopathology; Lung/blood supply; Lung/metabolism; Lung Compliance/drug effects; Male; Pulmonary Circulation/drug effects; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A/metabolism; Receptor, Endothelin B/metabolism; Respiratory Mechanics/drug effects; Vascular Resistance/drug effects; Vasoconstriction/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Peptides, Cyclic / Piperidines / Vasoactive Intestinal Peptide / Endothelin A Receptor Antagonists / Endothelin B Receptor Antagonists / Hypertension, Pulmonary / Lung / Antihypertensive Agents Limits: Animals Language: En Journal: Exp Physiol Journal subject: FISIOLOGIA Year: 2008 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom

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