Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses.

Garbacz, Grzegorz; Wedemeyer, Ralph-Steven; Nagel, Stefan; Giessmann, Thomas; Mönnikes, Hubert; Wilson, Clive G; Siegmund, Werner; Weitschies, Werner

Garbacz, Grzegorz; Wedemeyer, Ralph-Steven; Nagel, Stefan; Giessmann, Thomas; Mönnikes, Hubert; Wilson, Clive G; Siegmund, Werner; Weitschies, Werner.

Affiliation

Garbacz G; Department of Biopharmaceutics and Pharmaceutical Technology, University of Greifswald, Greifswald, Germany.

Eur J Pharm Biopharm ; 70(2): 421-8, 2008 Oct.

Article in En | MEDLINE | ID: mdl-18582568

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Diclofenac/administration & dosage; Absorption; Adult; Delayed-Action Preparations; Diclofenac/chemistry; Diclofenac/pharmacokinetics; Female; Humans; Male; Solubility; Tablets

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Diclofenac Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Eur J Pharm Biopharm Journal subject: FARMACIA / FARMACOLOGIA Year: 2008 Document type: Article Affiliation country: Germany Country of publication: Netherlands

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