The ubiquitin-proteasome pathway mediates gelsolin protein downregulation in pancreatic cancer.

Ni, Xiao-Guang; Zhou, Lu; Wang, Gui-Qi; Liu, Shang-Mei; Bai, Xiao-Feng; Liu, Fang; Peppelenbosch, Maikel P; Zhao, Ping

Ni, Xiao-Guang; Zhou, Lu; Wang, Gui-Qi; Liu, Shang-Mei; Bai, Xiao-Feng; Liu, Fang; Peppelenbosch, Maikel P; Zhao, Ping.

Affiliation

Ni XG; Department of Endoscopy, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Mol Med ; 14(9-10): 582-9, 2008.

Article in En | MEDLINE | ID: mdl-18584046

Subject(s)

Adenocarcinoma/pathology; Carcinoma, Pancreatic Ductal/pathology; Down-Regulation; Gelsolin/metabolism; Pancreatic Neoplasms/pathology; Proteasome Endopeptidase Complex/metabolism; Ubiquitin/metabolism; Adenocarcinoma/metabolism; Carcinoma, Pancreatic Ductal/metabolism; Cell Line, Tumor; Gelsolin/genetics; Humans; Immunohistochemistry; Oligonucleotide Array Sequence Analysis/methods; Pancreas/metabolism; Pancreas/pathology; Pancreatic Ducts/metabolism; Pancreatic Ducts/pathology; Pancreatic Neoplasms/metabolism; Proteasome Endopeptidase Complex/genetics; Proteomics; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Ubiquitin/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma / Down-Regulation / Gelsolin / Carcinoma, Pancreatic Ductal / Ubiquitin / Proteasome Endopeptidase Complex Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2008 Document type: Article Affiliation country: China Country of publication: United kingdom

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