Receptor activity-modifying proteins differentially modulate the G protein-coupling efficiency of amylin receptors.

Morfis, Maria; Tilakaratne, Nanda; Furness, Sebastian G B; Christopoulos, George; Werry, Tim D; Christopoulos, Arthur; Sexton, Patrick M

Morfis, Maria; Tilakaratne, Nanda; Furness, Sebastian G B; Christopoulos, George; Werry, Tim D; Christopoulos, Arthur; Sexton, Patrick M.

Affiliation

Morfis M; Drug Discovery Biology Laboratory, Monash Institute of Pharmaceutical Sciences, and Department of Pharmacology, Monash University, Clayton, Victoria 3800, Australia.

Endocrinology ; 149(11): 5423-31, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18599553

Subject(s)

GTP-Binding Proteins/metabolism; Intracellular Signaling Peptides and Proteins/physiology; Membrane Proteins/physiology; Receptors, Peptide/metabolism; Amyloid/metabolism; Animals; COS Cells; Chlorocebus aethiops; Cyclic AMP/metabolism; Humans; Islet Amyloid Polypeptide; Protein Binding; Rats; Receptor Activity-Modifying Protein 1; Receptor Activity-Modifying Protein 3; Receptor Activity-Modifying Proteins; Receptors, Calcitonin/metabolism; Receptors, G-Protein-Coupled/metabolism; Receptors, Islet Amyloid Polypeptide; Signal Transduction/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Peptide / GTP-Binding Proteins / Intracellular Signaling Peptides and Proteins / Membrane Proteins Limits: Animals / Humans Language: En Journal: Endocrinology Year: 2008 Document type: Article Affiliation country: Australia Country of publication: United States

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